A terminally ill cancer patient is attended throughout his final days by his wife and daughter while the trio contemplates their relationships with an estranged son, a situation that stirs up painful memories for a new next-door neighbor who has recently lost her mother.

In the community of Holt, Colorado, Victoria Roubideaux goes to college, leaving the McPheron brothers, who took her in when she was pregnant; DJ, a boy who lives alone with his grandfather, befriends two sisters whose father left them; and the children of a disabled couple face harassment at school.