Despite his overwhelming fear of interacting with people, Christopher, a mathematically-gifted, autistic fifteen-year-old boy, decides to investigate the murder of a neighbor's dog and uncovers secret information about his mother. Christopher John Francis Boone knows all the countries of the world and their capitals and every prime number up to 7,057. He relates well to animals but has no understanding of human emotions. He cannot stand to be touched....

"All the world is a puzzle, and Mike Brink-a celebrated and ingenious puzzle constructor-understands its patterns like no one else. Once a promising Midwestern football star, Brink was transformed by a traumatic brain injury that caused a rare medical condition: Acquired Savant Syndrome. The injury left him with a mental superpower-he can solve puzzles, calculate equations, and see patterns in ways ordinary people can't. But his condition has also...

The show is about a young surgeon with autism who is recruited to work at a pediatric unit of a hospital. The hospital is prestigious with many of the toughest cases a surgeon could ever see, but with autism comes clarity that most surgeons will never have. The television series focuses on the relationship between the doctor and patient, and how a man who cannot relate to the people who he tries to help.